PAGE2

Across TCGA patient cohorts, PAGE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,028 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PAGE2-associated GO terms across cancer lineages are Regulation of DNA replication, DNA-templated transcription elongation, and Methylation. Each is linked with PAGE2 in more than 15 cancer types. Because this analysis shows association rather than direction, both PAGE2-to-partner and partner-to-PAGE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA replication grouped by PAGE2-low versus PAGE2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE2→partner) and Y-score (partner→PAGE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA replication →	+0.088	+0.779	<.001	<.001	3	16
STAD	DNA-templated transcription elongation →	+0.069	+0.560	<.001	<.001	3	16
STAD	Methylation →	+0.052	+0.585	<.001	<.001	3	16
STAD	Positive regulation of DNA metabolic process →	+0.061	+0.564	<.001	<.001	3	16
STAD	Positive regulation of DNA repair →	+0.057	+0.613	<.001	<.001	3	15
STAD	Macromolecule methylation →	+0.077	+0.810	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,028 associations by consensus.

Regulation of DNA replication by PAGE2 expression — STAD

Explore this box plot interactively →