PAGE2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PAGE2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,551 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PAGE2-associated genes across cancer lineages are MTRNR2L2, OR52E7P, and CSAG1. Each is linked with PAGE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAGE2-to-partner and partner-to-PAGE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAGE2 versus MTRNR2L2 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE2→partner) and Y-score (partner→PAGE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMTRNR2L2 →+2.961+2.201<.001.00132
LUADOR52E7P →+0.875+2.606.009<.00132
LUADCSAG1 →+3.074+3.144<.001<.00132
LUADMIR105-1 →+0.824+4.468.005<.00132
LSCCZEB2P1 →+0.456+1.535.003.00632
LUADLINC02444 →+0.580+3.166.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,551 associations by consensus.

PAGE2 vs MTRNR2L2 — BRCA

Per-sample scatter of PAGE2 vs MTRNR2L2 in BRCA (Pearson r = 0.46).

Explore this scatter interactively →

Exploration