PAFAH1B3

Across TCGA patient cohorts, PAFAH1B3 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,556 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PAFAH1B3-associated proteins across cancer lineages are POLD1, XRCC1, and MCM2_S139. Each is linked with PAFAH1B3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PAFAH1B3-to-partner and partner-to-PAFAH1B3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAFAH1B3 versus POLD1 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAFAH1B3→partner) and Y-score (partner→PAFAH1B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	POLD1 →	+0.393	+0.708	.001	<.001	3	7
BRCA	XRCC1 →	+0.420	+0.831	<.001	<.001	3	7
LSCC	MCM2_S139 →	+0.711	+0.796	<.001	<.001	3	7
UCEC	MCM3 →	+0.590	+1.071	<.001	<.001	3	7
UCEC	MCM7 →	+0.617	+1.159	<.001	<.001	3	7
LSCC	FEN1 →	+0.506	+0.697	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,556 associations by consensus.

PAFAH1B3 vs POLD1 — LSCC

Explore this scatter interactively →