PAFAH1B1

Across TCGA cell cohorts, PAFAH1B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,805 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PAFAH1B1-associated GO terms across cancer lineages are Corpus callosum morphogenesis, Negative regulation of telomere capping, and Regulation of hippo signaling. Each is linked with PAFAH1B1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PAFAH1B1-to-partner and partner-to-PAFAH1B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Corpus callosum morphogenesis grouped by PAFAH1B1-low versus PAFAH1B1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAFAH1B1→partner) and Y-score (partner→PAFAH1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Corpus callosum morphogenesis →	+0.159	+0.902	<.001	<.001	3	17
OESOPHAGUS	Negative regulation of telomere capping →	+0.114	+0.752	.001	.006	3	14
BONE	Regulation of hippo signaling →	+0.094	+0.615	<.001	<.001	3	14
BREAST	Regulation of translation at synapse, modulating synaptic transmission →	+0.133	+0.927	<.001	<.001	3	13
OESOPHAGUS	Mitotic centrosome separation →	+0.126	+0.913	.001	<.001	3	13
OESOPHAGUS	RNA localization →	+0.101	+0.636	.001	.006	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,805 associations by consensus.

Corpus callosum morphogenesis by PAFAH1B1 expression — URINARY_TRACT

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