PADI4

Across TCGA patient cohorts, PADI4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,969 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PADI4-associated proteins across cancer lineages are PGLYRP1, UNC13D, and S100A12. Each is linked with PADI4 in more than 6 cancer types. Because this analysis shows association rather than direction, both PADI4-to-partner and partner-to-PADI4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PADI4 versus PGLYRP1 in PDAC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PADI4→partner) and Y-score (partner→PADI4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PGLYRP1 →	+1.347	+0.440	<.001	.005	3	7
OV	UNC13D →	+0.467	+0.267	.001	<.001	3	7
GBM	S100A12 →	+1.538	+0.581	<.001	<.001	3	7
GBM	CAMP →	+1.909	+0.450	<.001	<.001	3	7
GBM	ELANE →	+1.143	+0.499	<.001	<.001	3	7
GBM	ITGA2B →	+0.915	+0.521	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,969 associations by consensus.

PADI4 vs PGLYRP1 — PDAC

Explore this scatter interactively →