PACSIN1

Across TCGA patient cohorts, PACSIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,845 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PACSIN1-associated genes across cancer lineages are BCL2L14, IGF2BP2-AS1, and TCL1A. Each is linked with PACSIN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PACSIN1-to-partner and partner-to-PACSIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PACSIN1 versus BCL2L14 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PACSIN1→partner) and Y-score (partner→PACSIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BCL2L14 →	+0.827	+0.730	.002	<.001	3	4
LSCC	IGF2BP2-AS1 →	-1.202	-0.540	.002	.001	3	4
HNSC	TCL1A →	+0.848	+0.583	<.001	<.001	3	4
GBM	PPP1R16B →	+1.483	+0.856	<.001	<.001	3	4
HNSC	FCER2 →	+0.556	+0.475	.001	<.001	3	4
HNSC	RASSF4 →	+0.937	+0.870	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,845 associations by consensus.

PACSIN1 vs BCL2L14 — OV

Explore this scatter interactively →