PACRG

Across TCGA patient cohorts, PACRG protein abundance is significantly associated with the RNA expression of many other genes, with 6,430 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PACRG-associated genes across cancer lineages are RASL12, CCDC114, and C6orf118. Each is linked with PACRG in more than 2 cancer types. Because this analysis shows association rather than direction, both PACRG-to-partner and partner-to-PACRG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PACRG versus RASL12 in LUAD, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PACRG→partner) and Y-score (partner→PACRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RASL12 →	+0.663	+0.708	.001	<.001	3	3
UCEC	CCDC114 →	+2.111	+1.863	.002	.003	3	3
UCEC	C6orf118 →	+2.800	+1.788	.008	.006	3	3
BRCA	ITIH5 →	+1.103	+1.127	<.001	<.001	3	3
UCEC	C20orf85 →	+4.417	+1.896	.001	.005	3	3
UCEC	TTLL9 →	+1.514	+1.761	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,430 associations by consensus.

PACRG vs RASL12 — LUAD

Explore this scatter interactively →