PACRG

Across TCGA cell cohorts, PACRG RNA expression is significantly associated with the go_rna of many other GO terms, with 1,193 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PACRG-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Microtubule-based transport, and Transport along microtubule. Each is linked with PACRG in more than 7 cancer types. Because this analysis shows association rather than direction, both PACRG-to-partner and partner-to-PACRG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by PACRG-low versus PACRG-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PACRG→partner) and Y-score (partner→PACRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of syncytium formation by plasma membrane fusion →	+0.056	+0.132	<.001	<.001	3	8
OESOPHAGUS	Microtubule-based transport →	+0.046	+0.457	<.001	.002	3	7
OESOPHAGUS	Transport along microtubule →	+0.048	+0.457	<.001	.002	3	7
URINARY_TRACT	Energy derivation by oxidation of organic compounds →	+0.030	+0.309	.002	.002	3	7
BLOOD_Leukemia	Regulation of myoblast fusion →	+0.058	+0.107	<.001	.005	3	6
LUNG_NSCLC_LUAD	Negative regulation of myoblast fusion →	+0.063	+0.188	<.001	.006	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,193 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by PACRG expression — BLOOD_Leukemia

Explore this box plot interactively →