Across TCGA pan-cancer cohorts, PABPN1L Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PABPN1L data layer compared with 23 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher PABPN1L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PABPN1L expression acts as an unfavorable survival marker.

THYM and UCEC are the cancer types where PABPN1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: PABPN1L tumor-vs-normal RNA expression · all PABPN1L data types