PABPN1

Across TCGA patient cohorts, PABPN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,139 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PABPN1-associated proteins across cancer lineages are SUPT16H, APEX1, and SSRP1. Each is linked with PABPN1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PABPN1-to-partner and partner-to-PABPN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PABPN1 versus SUPT16H in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPN1→partner) and Y-score (partner→PABPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUPT16H →	+0.457	+0.438	<.001	<.001	3	8
GBM	APEX1 →	+0.377	+0.472	<.001	<.001	3	7
LSCC	SSRP1 →	+0.476	+0.426	<.001	<.001	3	6
PDAC	FKBP3 →	+0.314	+0.353	<.001	<.001	3	6
LSCC	CHD8 →	+0.270	+0.401	<.001	<.001	3	6
GBM	ACIN1 →	+0.240	+0.429	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,139 associations by consensus.

PABPN1 vs SUPT16H — LSCC

Explore this scatter interactively →