PABPC4L

Across TCGA cell cohorts, PABPC4L mutation is significantly associated with the mutation status of many other genes, with 116 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PABPC4L-associated genes across cancer lineages are DENND1A, LRPPRC, and KCTD13. Each is linked with PABPC4L in more than 1 cancer types. Because this analysis shows association rather than direction, both PABPC4L-to-partner and partner-to-PABPC4L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DENND1A grouped by PABPC4L-low versus PABPC4L-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC4L→partner) and Y-score (partner→PABPC4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DENND1A →	+4.502	+5.066	.007	.007	1	2
LUNG_NSCLC_LUAD	LRPPRC →	+4.339	+4.339	.009	.009	1	2
LUNG_NSCLC_LUAD	KCTD13 →	+4.339	+4.339	.009	.009	1	1
LUNG_NSCLC_LUAD	ZDHHC21 →	+5.339	+4.772	.004	.004	1	1
LUNG_NSCLC_LUAD	TSPEAR →	+3.924	+5.063	.001	.001	1	1
LUNG_NSCLC_LUAD	KIAA2026 →	+2.754	+4.189	.008	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

DENND1A by PABPC4L expression — LUNG_SCLC

Explore this box plot interactively →