PABPC1P4

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PABPC1P4 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated PABPC1P4 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PABPC1P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PABPC1P4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and COAD show a favorable association.

STAD, OV, and SKCM are the cancer types where PABPC1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSMedianAll0.4600.611.01145view →
OVOSMedianAll0.2580.369<.00138view →
SKCMOSQuartileIII,IV0.6080.343.00133view →
COADOSTertileAll0.8680.510.00331view →
KIRCDFSQuartileIII,IV0.6260.339.00128view →
KIRPDFSMedianIV0.0390.593.00824view →
HNSCDFSTertileIV0.5050.283.00421view →
BLCADFSQuartileIII,IV0.6620.471.00421view →
UCSDFSMedianIV0.9090.416.00818view →
SARCOSQuartileAll0.8860.629.00217view →
BRCAOSMedianIII,IV0.6300.453.01416view →
ESCAOSQuartileIII,IV0.7910.389.00415view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

PABPC1P4–STAD (DFS)

Kaplan–Meier survival curve for PABPC1P4 RNA-high vs -low samples in STAD.

Open the STAD breakdown →

Exploration