PABPC1P4

Across TCGA pan-cancer cohorts, PABPC1P4 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of PABPC1P4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where PABPC1P4 RNA is repressed in tumor relative to normal tissue. In most cancer types PABPC1P4 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and BLCA are the cancer types where PABPC1P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PABPC1P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	IV	−2.080	<.001	11	view →
KIRC	Male	IV	−1.138	<.001	11	view →
BLCA	Male	III,IV	−2.124	<.001	8	view →
KIRP	Female	II,III,IV	−1.889	<.001	7	view →
THCA	Male	All	−1.248	<.001	7	view →
UCEC	All	All	−1.520	<.001	6	view →
BRCA	Female	All	−1.219	<.001	6	view →
COAD	Female	All	+0.966	.001	5	view →
ESCA	All	II,III,IV	−1.380	.025	2	view →
PRAD	All	All	−0.886	<.001	2	view →
LUSC	All	All	−0.243	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

PABPC1P4–KICH

Open the KICH breakdown →