Across TCGA pan-cancer cohorts, PABPC1L2B-AS1 RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated PABPC1L2B-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PABPC1L2B-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PABPC1L2B-AS1 expression acts as an unfavorable survival marker, although some lineages such as LIHC and LGG show a favorable association.

KIRC, UCEC, and LIHC are the cancer types where PABPC1L2B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.226	0.623	.032	18	view →
UCEC	DFS	Tertile	All	0.694	0.899	.022	12	view →
LIHC	DFS	Tertile	II,III,IV	1.000	0.312	.021	12	view →
LGG	OS	Tertile	All	0.931	0.883	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: PABPC1L2B-AS1 tumor-vs-normal RNA expression · all PABPC1L2B-AS1 data types