Across TCGA patient cohorts, PABPC1L2A mutation is significantly associated with the RNA expression of many other genes, with 130 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC1L2A-associated genes across cancer lineages are MIR129-2, RNU6-446P, and SDCBP2P1. Each is linked with PABPC1L2A in more than 1 cancer types. Because this analysis shows association rather than direction, both PABPC1L2A-to-partner and partner-to-PABPC1L2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1L2A→partner) and Y-score (partner→PABPC1L2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR129-2 →	+0.354	+6.409	<.001	<.001	3	1
COAD	RNU6-446P →	+0.606	+4.354	.007	.007	3	1
COAD	SDCBP2P1 →	+0.069	+5.917	<.001	.001	3	1
COAD	LINC01523 →	+0.311	+5.484	<.001	<.001	3	1
COAD	CNOT7P2 →	+0.106	+5.081	.002	.001	3	1
COAD	LINC01621 →	+0.091	+5.251	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 130 associations by consensus.

Exploration

PABPC1L2A survival (RNA) · tumor vs normal (RNA) · all PABPC1L2A data types