PAAF1

Across TCGA patient cohorts, PAAF1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,297 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PAAF1-associated genes across cancer lineages are SF3B2, PPME1, and CLNS1A. Each is linked with PAAF1 in more than 33 cancer types. Because this analysis shows association rather than direction, both PAAF1-to-partner and partner-to-PAAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAAF1 versus SF3B2 in ACC, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAAF1→partner) and Y-score (partner→PAAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	SF3B2 →	+1.260	+1.012	<.001	<.001	3	34
ACC	PPME1 →	+0.942	+0.957	<.001	<.001	3	33
ACC	CLNS1A →	+0.968	+1.000	<.001	<.001	3	33
ACC	INTS4 →	+1.114	+1.109	<.001	<.001	3	33
ACC	DDB1 →	+1.058	+0.801	<.001	<.001	3	33
ACC	METTL23 →	+1.070	+0.983	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,297 associations by consensus.

PAAF1 vs SF3B2 — ACC

Explore this scatter interactively →