PAAF1

Across TCGA patient cohorts, PAAF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,950 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PAAF1-associated proteins across cancer lineages are MRE11, PPME1, and NUMA1. Each is linked with PAAF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PAAF1-to-partner and partner-to-PAAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAAF1 versus MRE11 in COAD, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAAF1→partner) and Y-score (partner→PAAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MRE11 →	+0.292	+0.334	<.001	<.001	3	7
BRCA	PPME1 →	+0.317	+0.371	<.001	<.001	3	6
LSCC	NUMA1 →	+0.393	+0.496	<.001	<.001	3	6
CCRCC	ARPC2 →	-0.239	-0.474	<.001	<.001	3	5
GBM	CDA →	-1.020	-0.363	<.001	<.001	3	5
OV	RSF1 →	+0.374	+0.501	.007	.002	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,950 associations by consensus.

PAAF1 vs MRE11 — COAD

Explore this scatter interactively →