PAAF1

Across TCGA patient cohorts, PAAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,800 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PAAF1-associated genes across cancer lineages are KTN1, RNU6-932P, and GNPDA1. Each is linked with PAAF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PAAF1-to-partner and partner-to-PAAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAAF1 versus KTN1 in OV, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAAF1→partner) and Y-score (partner→PAAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KTN1 →	-0.538	-0.320	.009	.003	3	5
GBM	RNU6-932P →	-0.794	-0.293	.007	.001	3	4
UCEC	GNPDA1 →	+0.533	+0.319	<.001	<.001	3	3
UCEC	FAAP24 →	+0.364	+0.199	.009	.001	2	4
UCEC	NEU3 →	+0.388	+0.220	.007	.001	3	3
BRCA	RNF169 →	+0.611	+0.270	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,800 associations by consensus.

PAAF1 vs KTN1 — OV

Explore this scatter interactively →