P4HA3

Across TCGA cell cohorts, P4HA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,738 significant associations in total. BONE shows the largest number of these associations.

The most reproducible P4HA3-associated GO terms across cancer lineages are Regulation of protein K48-linked ubiquitination, Protein folding, and Wound healing, spreading of epidermal cells. Each is linked with P4HA3 in more than 11 cancer types. Because this analysis shows association rather than direction, both P4HA3-to-partner and partner-to-P4HA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein K48-linked ubiquitination grouped by P4HA3-low versus P4HA3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P4HA3→partner) and Y-score (partner→P4HA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protein K48-linked ubiquitination →	+0.160	+0.488	<.001	.001	3	12
SKIN	Protein folding →	+0.066	+0.951	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Wound healing, spreading of epidermal cells →	+0.177	+1.286	.003	.002	3	11
BONE	Regulation of cell-substrate junction organization →	+0.117	+1.735	.007	.003	3	11
BONE	Positive regulation of cell-substrate junction organization →	+0.154	+1.815	.001	.002	3	11
BONE	Positive regulation of focal adhesion assembly →	+0.177	+1.779	.002	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,738 associations by consensus.

Regulation of protein K48-linked ubiquitination by P4HA3 expression — STOMACH

Explore this box plot interactively →