P4HA3-AS1

Across TCGA pan-cancer cohorts, P4HA3-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated P4HA3-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher P4HA3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated P4HA3-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

BLCA, UVM, and UCS are the cancer types where P4HA3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.521	0.648	.001	88	view →
UVM	DFS	Tertile	All	0.522	0.802	.008	43	view →
UCS	DFS	Tertile	IV	0.981	0.510	.020	38	view →
STAD	DFS	Quartile	All	0.531	0.806	.003	24	view →
THYM	OS	Tertile	III,IV	0.615	1.000	.019	18	view →
LGG	DFS	Tertile	All	0.663	0.776	.005	14	view →
ACC	OS	Quartile	All	0.360	0.760	.011	12	view →
KIRP	OS	Tertile	II,III,IV	0.469	0.790	.045	9	view →
LUAD	OS	Quartile	II,III,IV	0.599	0.734	.012	9	view →
ESCA	OS	Tertile	All	0.574	0.766	.009	8	view →
CHOL	DFS	Median	III,IV	0.133	0.779	.038	6	view →
BRCA	DFS	Tertile	III,IV	0.666	0.386	.027	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

P4HA3-AS1–BLCA (DFS)

Open the BLCA breakdown →