P4HA3-AS1

Across TCGA pan-cancer cohorts, P4HA3-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of P4HA3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where P4HA3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types P4HA3-AS1 is over-expressed in tumor.

KIRC, HNSC, and LUAD are the cancer types where P4HA3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in P4HA3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.022	<.001	8	view →
HNSC	All	All	+0.023	.005	7	view →
LUAD	Female	All	+0.030	.016	3	view →
STAD	Male	All	+0.040	.004	2	view →
KICH	All	II,III,IV	+0.016	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

P4HA3-AS1–KIRC

Open the KIRC breakdown →