P4HA2-AS1

Across TCGA pan-cancer cohorts, P4HA2-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated P4HA2-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher P4HA2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated P4HA2-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUAD show a favorable association.

HNSC, UVM, and BLCA are the cancer types where P4HA2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.379	0.597	.004	44	view →
UVM	DFS	Quartile	All	0.213	0.825	.007	36	view →
BLCA	OS	Median	IV	0.536	0.236	.014	12	view →
CESC	OS	Tertile	III,IV	0.598	0.860	.021	10	view →
ACC	OS	Quartile	II,III,IV	0.416	0.904	.020	10	view →
MESO	DFS	Tertile	IV	0.281	0.705	.031	9	view →
LUAD	DFS	Median	IV	0.721	0.275	.015	7	view →
CHOL	OS	Median	IV	1.000	0.286	.024	7	view →
ESCA	DFS	Median	All	0.544	0.912	.038	6	view →
BRCA	DFS	Median	III,IV	0.923	0.835	.008	6	view →
OV	DFS	Tertile	IV	0.343	0.532	.026	6	view →
THCA	DFS	Tertile	IV	0.662	0.909	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

P4HA2-AS1–HNSC (DFS)

Open the HNSC breakdown →