P3R3URF-PIK3R3

Across TCGA patient cohorts, P3R3URF-PIK3R3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,753 significant associations in total. STAD shows the largest number of these associations.

The most reproducible P3R3URF-PIK3R3-associated GO terms across cancer lineages are Cytoskeleton-dependent cytokinesis, Midbody abscission, and Golgi organization. Each is linked with P3R3URF-PIK3R3 in more than 5 cancer types. Because this analysis shows association rather than direction, both P3R3URF-PIK3R3-to-partner and partner-to-P3R3URF-PIK3R3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent cytokinesis grouped by P3R3URF-PIK3R3-low versus P3R3URF-PIK3R3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P3R3URF-PIK3R3→partner) and Y-score (partner→P3R3URF-PIK3R3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cytoskeleton-dependent cytokinesis →	+0.121	+0.005	<.001	.001	3	6
ESCA	Midbody abscission →	+0.105	+0.008	<.001	.001	3	6
STAD	Golgi organization →	+0.107	+0.014	<.001	<.001	3	6
STAD	Protein autophosphorylation →	+0.102	+0.012	<.001	<.001	3	5
STAD	Cellular response to acid chemical →	+0.095	+0.014	<.001	<.001	3	5
STAD	Myotube differentiation →	+0.058	+0.016	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,753 associations by consensus.

Cytoskeleton-dependent cytokinesis by P3R3URF-PIK3R3 expression — ESCA

Explore this box plot interactively →