P3R3URF-PIK3R3

Across TCGA pan-cancer cohorts, P3R3URF-PIK3R3 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated P3R3URF-PIK3R3 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher P3R3URF-PIK3R3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated P3R3URF-PIK3R3 expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

KIRP, UCEC, and OV are the cancer types where P3R3URF-PIK3R3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	II,III,IV	0.148	0.771	<.001	54	view →
UCEC	OS	Tertile	III,IV	0.054	0.588	.007	36	view →
OV	DFS	Tertile	All	0.321	0.150	.027	36	view →
KICH	OS	Tertile	II,III,IV	0.834	1.000	.002	32	view →
ESCA	DFS	Tertile	III,IV	0.777	0.269	.030	27	view →
LUSC	OS	Tertile	All	0.288	0.728	.019	18	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →
HNSC	OS	Tertile	All	0.268	0.713	.009	18	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	18	view →
SARC	DFS	Tertile	All	0.138	0.635	.001	9	view →
STAD	DFS	Tertile	All	0.490	0.724	.043	9	view →
THCA	DFS	Tertile	All	0.751	0.945	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

P3R3URF-PIK3R3–KIRP (OS)

Open the KIRP breakdown →