P2RY6

Across TCGA patient cohorts, P2RY6 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,341 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible P2RY6-associated proteins across cancer lineages are LCP2, PARP14, and PARVG. Each is linked with P2RY6 in more than 9 cancer types. Because this analysis shows association rather than direction, both P2RY6-to-partner and partner-to-P2RY6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RY6 versus LCP2 in BRCA, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY6→partner) and Y-score (partner→P2RY6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LCP2 →	+0.529	+1.083	<.001	<.001	3	10
OV	PARP14 →	+0.441	+1.241	.002	<.001	3	10
CCRCC	PARVG →	+0.686	+1.071	<.001	<.001	3	10
CCRCC	SAMSN1 →	+0.748	+1.273	<.001	<.001	3	9
UCEC	THEMIS2 →	+0.617	+1.150	<.001	<.001	3	9
UCEC	CARD9_S460 →	+0.852	+0.928	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,341 associations by consensus.

P2RY6 vs LCP2 — BRCA

Explore this scatter interactively →