P2RY6

Across TCGA cell cohorts, P2RY6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,799 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible P2RY6-associated GO terms across cancer lineages are Cell-substrate junction assembly, Substrate adhesion-dependent cell spreading, and Protein targeting to vacuole involved in autophagy. Each is linked with P2RY6 in more than 9 cancer types. Because this analysis shows association rather than direction, both P2RY6-to-partner and partner-to-P2RY6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction assembly grouped by P2RY6-low versus P2RY6-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY6→partner) and Y-score (partner→P2RY6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cell-substrate junction assembly →	+0.168	+1.356	.006	.002	3	10
BONE	Substrate adhesion-dependent cell spreading →	+0.144	+0.633	<.001	.009	3	10
LUNG_NSCLC_LUSC	Protein targeting to vacuole involved in autophagy →	+0.205	+1.475	.002	.006	3	9
BONE	Response to hypoxia →	+0.081	+1.118	<.001	.008	3	9
UPPER_AERODIGESTIVE_TRACT	Protein localization to endoplasmic reticulum →	+0.103	+1.670	.002	.002	3	9
STOMACH	Mannose metabolic process →	+0.132	+1.292	.001	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,799 associations by consensus.

Cell-substrate junction assembly by P2RY6 expression — STOMACH

Explore this box plot interactively →