P2RY14

Across TCGA pan-cancer cohorts, P2RY14 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated P2RY14 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher P2RY14 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated P2RY14 expression acts as an unfavorable survival marker.

LUSC are the cancer types where P2RY14 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	II,III,IV	0.079	0.750	<.001	21	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

P2RY14–LUSC (DFS)

Open the LUSC breakdown →