P2RY14

Across TCGA cell cohorts, P2RY14 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible P2RY14-associated genes across cancer lineages are SLC35G3, C1orf68, and LCE1F. Each is linked with P2RY14 in more than 1 cancer types. Because this analysis shows association rather than direction, both P2RY14-to-partner and partner-to-P2RY14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC35G3 grouped by P2RY14-low versus P2RY14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY14→partner) and Y-score (partner→P2RY14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC35G3 →	+0.006	+4.467	.007	.004	3	1
LARGE_INTESTINE	C1orf68 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	LCE1F →	+0.106	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CCDC179 →	+0.056	+4.095	.006	.009	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

SLC35G3 by P2RY14 expression — LARGE_INTESTINE

Explore this box plot interactively →