P2RY13

Across TCGA patient cohorts, P2RY13 mutation is significantly associated with the RNA expression of many other genes, with 1,037 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible P2RY13-associated genes across cancer lineages are THAP12P4, RN7SKP265, and NFYAP1. Each is linked with P2RY13 in more than 1 cancer types. Because this analysis shows association rather than direction, both P2RY13-to-partner and partner-to-P2RY13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, THAP12P4 grouped by P2RY13-low versus P2RY13-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY13→partner) and Y-score (partner→P2RY13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	THAP12P4 →	+0.031	+5.788	<.001	.003	3	2
COAD	RN7SKP265 →	+0.370	+5.409	<.001	.001	3	2
CESC	NFYAP1 →	+0.239	+5.010	<.001	.009	3	2
CESC	SNORD3C →	+0.066	+5.812	<.001	.003	3	2
UCEC	RNU6-42P →	+0.524	+2.156	.006	.004	3	2
UCEC	RN7SL97P →	+0.112	+2.446	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,037 associations by consensus.

THAP12P4 by P2RY13 expression — BLCA

Explore this box plot interactively →