P2RY11

Across TCGA pan-cancer cohorts, P2RY11 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated P2RY11 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher P2RY11 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated P2RY11 expression acts as an unfavorable survival marker.

KIRC, CHOL, and SKCM are the cancer types where P2RY11 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.167	0.655	.038	12	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →
SKCM	OS	Median	III,IV	0.179	0.721	.006	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

P2RY11–KIRC (OS)

Open the KIRC breakdown →