P2RY1

Across TCGA cell cohorts, P2RY1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible P2RY1-associated genes across cancer lineages are OR2T4 and CCL18. Each is linked with P2RY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both P2RY1-to-partner and partner-to-P2RY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T4 grouped by P2RY1-low versus P2RY1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY1→partner) and Y-score (partner→P2RY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR2T4 →	+0.062	+4.643	<.001	.004	3	1
LUNG_NSCLC_LUAD	CCL18 →	+0.034	+4.212	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2T4 by P2RY1 expression — LUNG_SCLC

Explore this box plot interactively →