P2RX7

Across TCGA patient cohorts, P2RX7 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,117 significant associations in total. GBM shows the largest number of these associations.

The most reproducible P2RX7-associated proteins across cancer lineages are APBB1IP, DOCK10, and ITGAL. Each is linked with P2RX7 in more than 9 cancer types. Because this analysis shows association rather than direction, both P2RX7-to-partner and partner-to-P2RX7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RX7 versus APBB1IP in UCEC, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX7→partner) and Y-score (partner→P2RX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	APBB1IP →	+0.592	+0.691	<.001	<.001	3	10
UCEC	DOCK10 →	+0.540	+0.705	<.001	<.001	3	9
UCEC	ITGAL →	+0.784	+0.832	<.001	<.001	3	9
UCEC	LCP2 →	+0.507	+0.666	<.001	<.001	3	9
UCEC	PLCB2 →	+0.381	+0.580	<.001	<.001	3	8
UCEC	MYO1F →	+0.482	+0.506	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,117 associations by consensus.

P2RX7 vs APBB1IP — UCEC

Explore this scatter interactively →