OXT

Across TCGA patient cohorts, OXT protein abundance is significantly associated with the RNA expression of many other genes, with 6,810 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OXT-associated genes across cancer lineages are SEC14L2, PPIL2, and CARD10. Each is linked with OXT in more than 1 cancer types. Because this analysis shows association rather than direction, both OXT-to-partner and partner-to-OXT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OXT versus SEC14L2 in BRCA, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXT→partner) and Y-score (partner→OXT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEC14L2 →	-1.408	-1.402	<.001	<.001	3	1
BRCA	PPIL2 →	-0.665	-1.404	<.001	<.001	3	1
BRCA	CARD10 →	-1.069	-1.238	<.001	<.001	3	1
BRCA	GRK3 →	-0.640	-0.784	<.001	<.001	3	1
BRCA	HPS4 →	-0.419	-0.950	<.001	<.001	3	1
BRCA	PIK3IP1 →	-1.031	-1.219	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,810 associations by consensus.

OXT vs SEC14L2 — BRCA

Explore this scatter interactively →