OXT

Across TCGA patient cohorts, OXT mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXT-associated genes across cancer lineages are RNU6-471P, MIR495, and OR4A48P. Each is linked with OXT in more than 1 cancer types. Because this analysis shows association rather than direction, both OXT-to-partner and partner-to-OXT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-471P grouped by OXT-low versus OXT-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXT→partner) and Y-score (partner→OXT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-471P →	+0.228	+7.640	<.001	.009	3	1
BLCA	MIR495 →	+0.228	+7.640	<.001	.009	3	1
BLCA	OR4A48P →	+0.068	+7.640	<.001	.009	3	1
BLCA	OR4A41P →	+0.029	+7.640	<.001	.009	3	1
BLCA	MIR3142 →	+0.288	+7.640	<.001	.009	3	1
UCEC	RN7SL237P →	+0.361	+4.496	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

RNU6-471P by OXT expression — BLCA

Explore this box plot interactively →