OXSM

Across TCGA patient cohorts, OXSM protein abundance is significantly associated with the RNA expression of many other genes, with 7,700 significant associations in total. COAD shows the largest number of these associations.

The most reproducible OXSM-associated genes across cancer lineages are TOP2A, PLK4, and RACGAP1. Each is linked with OXSM in more than 4 cancer types. Because this analysis shows association rather than direction, both OXSM-to-partner and partner-to-OXSM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OXSM versus TOP2A in OV, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXSM→partner) and Y-score (partner→OXSM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TOP2A →	-0.977	-0.351	<.001	<.001	3	5
COAD	PLK4 →	-0.651	-0.258	<.001	<.001	3	5
OV	RACGAP1 →	-0.735	-0.437	.001	<.001	3	5
OV	SGO2 →	-0.696	-0.265	<.001	.008	3	5
COAD	ZWILCH →	-0.695	-0.279	<.001	.001	3	5
COAD	GABPB1 →	-0.470	-0.355	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,700 associations by consensus.

OXSM vs TOP2A — OV

Explore this scatter interactively →