OXSM

Across TCGA patient cohorts, OXSM mutation is significantly associated with the RNA expression of many other genes, with 3,216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXSM-associated genes across cancer lineages are UBE2CP4, RN7SL440P, and IGHD1-26. Each is linked with OXSM in more than 1 cancer types. Because this analysis shows association rather than direction, both OXSM-to-partner and partner-to-OXSM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2CP4 grouped by OXSM-low versus OXSM-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXSM→partner) and Y-score (partner→OXSM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	UBE2CP4 →	+0.127	+5.033	.002	.009	3	2
LIHC	RN7SL440P →	+0.378	+5.108	<.001	.008	3	2
UCEC	IGHD1-26 →	+0.500	+2.558	<.001	.002	3	2
UCEC	ATF4P1 →	+0.048	+2.132	<.001	.004	3	2
UCEC	TOMM22P5 →	+0.241	+1.954	<.001	.002	3	2
HNSC	KRTAP1-4 →	+0.125	+5.008	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,216 associations by consensus.

UBE2CP4 by OXSM expression — LIHC

Explore this box plot interactively →