OXER1

Across TCGA patient cohorts, OXER1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXER1-associated genes across cancer lineages are FoxM1, JNK_pT183_Y185, and PCNA. Each is linked with OXER1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXER1-to-partner and partner-to-OXER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by OXER1-low versus OXER1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXER1→partner) and Y-score (partner→OXER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.283	+2.321	.029	.035	3	2
UCEC	JNK_pT183_Y185 →	-0.172	-2.308	.042	.036	3	2
UCEC	PCNA →	+0.352	+3.169	.001	.019	3	2
UCEC	Caspase-7-cleavedD198 →	+1.278	+3.459	<.001	.005	3	2
UCEC	EGFR_pY1068 →	-0.250	-2.321	.047	.035	3	1
UCEC	A-Raf_pS299 →	-0.211	-2.999	<.001	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

FoxM1 by OXER1 expression — UCEC

Explore this box plot interactively →