OXER1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, OXER1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of OXER1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where OXER1 RNA is repressed in tumor relative to normal tissue. In most cancer types OXER1 is over-expressed in tumor, although a few such as BLCA and KICH show the opposite, repressed pattern.

BLCA, KICH, and KIRP are the cancer types where OXER1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OXER1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BLCAAllIV−1.942<.00111view →
KICHMaleII,III,IV−2.051<.0019view →
KIRPAllIII,IV−1.366.0027view →
UCECAllAll−1.276<.0016view →
BRCAAllIII,IV−0.817<.0016view →
CHOLAllAll−1.985<.0015view →
KIRCAllII,III,IV+0.458.0175view →
HNSCAllAll−0.396.0075view →
STADFemaleAll+1.137.0064view →
LIHCMaleII,III,IV−1.175.0152view →
PRADAllAll−0.909<.0012view →
LUSCMaleIII,IV−0.742.0222view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

OXER1–BLCA

Tumor-vs-normal expression box plot for OXER1 RNA in BLCA.

Open the BLCA breakdown →

Exploration