OXER1

Across TCGA cell cohorts, OXER1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,256 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OXER1-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, and mRNA splicing, via spliceosome. Each is linked with OXER1 in more than 6 cancer types. Because this analysis shows association rather than direction, both OXER1-to-partner and partner-to-OXER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA splicing, via transesterification reactions grouped by OXER1-low versus OXER1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OXER1→partner) and Y-score (partner→OXER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RNA splicing, via transesterification reactions →	+0.045	+0.636	.001	.001	3	7
SOFT_TISSUE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.066	+0.859	<.001	<.001	3	7
SOFT_TISSUE	mRNA splicing, via spliceosome →	+0.066	+0.859	<.001	<.001	3	7
LIVER	Dicarboxylic acid biosynthetic process →	-0.198	-1.323	.001	.001	3	6
SOFT_TISSUE	Transcription initiation at RNA polymerase II promoter →	+0.049	+0.734	<.001	.009	2	7
SOFT_TISSUE	Protein localization to cytoplasmic stress granule →	+0.078	+0.720	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,256 associations by consensus.

RNA splicing, via transesterification reactions by OXER1 expression — SOFT_TISSUE

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