OXCT1

Across TCGA patient cohorts, OXCT1 mutation is significantly associated with the RNA expression of many other genes, with 1,461 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXCT1-associated genes across cancer lineages are MIR188, RNU6-222P, and SNX3P1Y. Each is linked with OXCT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXCT1-to-partner and partner-to-OXCT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR188 grouped by OXCT1-low versus OXCT1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXCT1→partner) and Y-score (partner→OXCT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR188 →	+0.155	+4.733	.005	.004	3	2
BLCA	RNU6-222P →	+0.660	+4.213	<.001	.003	3	2
UCEC	SNX3P1Y →	+0.056	+3.620	<.001	.009	3	2
BLCA	LRRC6P1 →	+0.040	+4.562	<.001	.006	3	2
BLCA	MIR6769B →	+0.321	+5.455	<.001	.001	3	2
UCEC	RNA5SP411 →	+0.779	+1.531	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,461 associations by consensus.

MIR188 by OXCT1 expression — LUSC

Explore this box plot interactively →