OVOL1

Across TCGA cell cohorts, OVOL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,899 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OVOL1-associated GO terms across cancer lineages are Bundle of His cell to Purkinje myocyte communication, Desmosome assembly, and Desmosome organization. Each is linked with OVOL1 in more than 10 cancer types. Because this analysis shows association rather than direction, both OVOL1-to-partner and partner-to-OVOL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bundle of His cell to Purkinje myocyte communication grouped by OVOL1-low versus OVOL1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OVOL1→partner) and Y-score (partner→OVOL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Bundle of His cell to Purkinje myocyte communication →	+0.423	+1.784	.002	<.001	3	11
STOMACH	Desmosome assembly →	+0.411	+2.389	<.001	<.001	3	11
LUNG_SCLC	Desmosome organization →	+0.494	+1.296	.004	.001	3	11
LUNG_NSCLC_LUSC	Maintenance of blood-brain barrier →	+0.204	+1.494	<.001	<.001	3	11
OESOPHAGUS	Establishment or maintenance of epithelial cell apical/basal polarity →	+0.161	+2.493	.001	.001	3	11
STOMACH	Intracellular sodium ion homeostasis →	+0.247	+1.977	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,899 associations by consensus.

Bundle of His cell to Purkinje myocyte communication by OVOL1 expression — OVARY

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