OVOL1-AS1

Across TCGA pan-cancer cohorts, OVOL1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated OVOL1-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher OVOL1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated OVOL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and LGG show a favorable association.

KIRP, LGG, and PAAD are the cancer types where OVOL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Quartile	II,III,IV	0.869	0.485	.002	59	view →
LGG	OS	Median	All	0.870	0.746	<.001	39	view →
PAAD	OS	Tertile	All	0.372	0.590	.006	20	view →
HNSC	DFS	Median	IV	0.727	0.603	.021	18	view →
PCPG	DFS	Median	All	0.786	0.956	<.001	18	view →
ACC	DFS	Tertile	All	0.151	0.618	.003	18	view →
PRAD	DFS	Quartile	All	0.701	0.868	.004	16	view →
UCEC	DFS	Quartile	All	0.877	0.939	.011	14	view →
LIHC	OS	Tertile	All	0.404	0.643	.021	13	view →
MESO	OS	Tertile	III,IV	0.316	0.705	.036	9	view →
COAD	DFS	Quartile	All	0.396	0.691	.008	8	view →
LUSC	OS	Median	II,III,IV	0.518	0.326	.005	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

OVOL1-AS1–KIRP (OS)

Open the KIRP breakdown →