OVOL1-AS1

Across TCGA pan-cancer cohorts, OVOL1-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of OVOL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where OVOL1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types OVOL1-AS1 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where OVOL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OVOL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	−1.280	<.001	8	view →
KIRC	Male	III,IV	+1.033	<.001	7	view →
KICH	All	All	−0.766	<.001	7	view →
BRCA	All	II,III,IV	+0.331	<.001	6	view →
LUAD	All	All	+0.161	.002	5	view →
LUSC	Male	All	+0.541	<.001	4	view →
PAAD	All	All	+0.379	.027	2	view →
COAD	Female	All	−0.302	.019	2	view →
LIHC	All	All	+0.367	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

OVOL1-AS1–KIRP

Open the KIRP breakdown →