OVCA2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OVCA2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,901 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OVCA2-associated genes across cancer lineages are MXI1, TOP1MT, and FOXO4. Each is linked with OVCA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OVCA2-to-partner and partner-to-OVCA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OVCA2 versus MXI1 in LSCC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVCA2→partner) and Y-score (partner→OVCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMXI1 →-0.559-0.181<.001.00233
LSCCTOP1MT →-0.572-0.141<.001.00533
COADFOXO4 →-0.591-0.249<.001<.00133
COADZNF34 →-0.416-0.252<.001<.00133
HNSCSYNPR-AS1 →-0.814-0.276<.001<.00133
LSCCKDM7A-DT →-0.838-0.223<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,901 associations by consensus.

OVCA2 vs MXI1 — LSCC

Per-sample scatter of OVCA2 vs MXI1 in LSCC (Pearson r = -0.28).

Explore this scatter interactively →

Exploration