OVAAL

Across TCGA pan-cancer cohorts, OVAAL RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated OVAAL data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher OVAAL RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OVAAL expression acts as an unfavorable survival marker, although some lineages such as CESC and UCS show a favorable association.

STAD, UVM, and MESO are the cancer types where OVAAL RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	All	0.240	0.519	<.001	115	view →
UVM	OS	Tertile	III,IV	0.192	0.724	<.001	99	view →
MESO	OS	Median	III,IV	0.403	0.678	.001	50	view →
CESC	DFS	Median	IV	0.746	0.293	.002	34	view →
UCS	DFS	Median	IV	0.981	0.450	.004	18	view →
LUSC	DFS	Median	II,III,IV	0.530	0.288	.001	17	view →
LGG	OS	Quartile	All	0.305	0.468	.002	16	view →
BRCA	OS	Median	All	0.680	0.489	<.001	13	view →
KIRP	OS	Tertile	All	0.533	0.732	.035	12	view →
OV	DFS	Tertile	IV	0.373	0.638	.005	12	view →
HNSC	OS	Median	All	0.624	0.766	.009	11	view →
COAD	DFS	Tertile	IV	0.035	0.501	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

OVAAL–STAD (DFS)

Open the STAD breakdown →