Q-omics provides the consensus-scored OVAAL profile across patient tissues and cancer cell-line models. OVAAL expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, OVAAL is differentially expressed in 10, with the highest sampling consensus in KIRC. Additionally, OVAAL RNA expression shows 6,054 significant pathway-activity associations, with the highest sampling consensus in THCA. Together, these results highlight STAD, KIRC, and THCA as cancer lineages where OVAAL shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OVAAL — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OVAAL survival associations across molecular data types. OVAAL RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OVAAL RNA expression–survival associations across cancer types. High OVAAL expression shows unfavorable associations in STAD, UVM and MESO, but favorable associations in CESC, UCS and LUSC. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify STAD as the clearest survival context for OVAAL RNA expression.
This table summarizes OVAAL tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for OVAAL. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OVAAL shows lower tumor expression in KIRC, COAD, BRCA and KICH and higher tumor expression in THCA and UCEC. The KIRC box plot shows higher OVAAL RNA expression in normal versus tumor tissue (log2 FC = −0.030, t-test p < 0.001).
This table shows molecular features associated with OVAAL in patient tissues and cancer cell lines. In patient samples, OVAAL shows the broadest associations at the RNA and protein expression levels, with THCA recurring as the lineage with the largest associated feature set.
