OTX2-AS1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OTX2-AS1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated OTX2-AS1 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher OTX2-AS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OTX2-AS1 expression acts as an unfavorable survival marker.

UCEC are the cancer types where OTX2-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianAll0.2310.873<.00136view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

OTX2-AS1–UCEC (OS)

Kaplan–Meier survival curve for OTX2-AS1 mutant vs wild-type samples in UCEC.

Open the UCEC breakdown →

Exploration