OTX1

Across TCGA patient cohorts, OTX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,203 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OTX1-associated proteins across cancer lineages are XPO5, MVP, and TOP2A_S1247. Each is linked with OTX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both OTX1-to-partner and partner-to-OTX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTX1 versus XPO5 in BRCA, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OTX1→partner) and Y-score (partner→OTX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	XPO5 →	+0.648	+0.916	<.001	<.001	3	7
GBM	MVP →	-0.498	-1.100	.007	.002	3	6
BRCA	TOP2A_S1247 →	+1.193	+0.924	<.001	<.001	3	6
BRCA	TRMT6 →	+0.404	+0.886	<.001	<.001	3	6
PDAC	GINS3 →	+0.763	+0.335	<.001	<.001	3	6
BRCA	GMPS →	+0.366	+0.905	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,203 associations by consensus.

OTX1 vs XPO5 — BRCA

Explore this scatter interactively →