OTUD6B-AS1

Across TCGA pan-cancer cohorts, OTUD6B-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated OTUD6B-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher OTUD6B-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated OTUD6B-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LGG show a favorable association.

KIRC, UVM, and CESC are the cancer types where OTUD6B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.709	0.559	<.001	84	view →
UVM	DFS	Quartile	II,III,IV	0.251	0.715	<.001	84	view →
CESC	DFS	Tertile	All	0.665	0.847	.001	74	view →
KIRP	DFS	Median	All	0.783	0.942	<.001	36	view →
LIHC	OS	Median	All	0.367	0.668	<.001	36	view →
LGG	DFS	Tertile	All	0.669	0.400	<.001	30	view →
SKCM	DFS	Median	All	0.253	0.144	<.001	29	view →
BRCA	OS	Quartile	All	0.474	0.648	<.001	29	view →
OV	DFS	Quartile	IV	0.294	0.623	.001	20	view →
HNSC	OS	Quartile	All	0.249	0.563	.003	18	view →
MESO	OS	Median	II,III,IV	0.493	0.310	.011	16	view →
LUSC	DFS	Median	III,IV	0.339	0.883	.002	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

OTUD6B-AS1–KIRC (OS)

Open the KIRC breakdown →