Across TCGA cell cohorts, OTUD6A mutation is significantly associated with the RNA expression of many other genes, with 139 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OTUD6A-associated genes across cancer lineages are SPATA31D1, EIF3L, and HSCB. Each is linked with OTUD6A in more than 1 cancer types. Because this analysis shows association rather than direction, both OTUD6A-to-partner and partner-to-OTUD6A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD6A→partner) and Y-score (partner→OTUD6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SPATA31D1 →	+0.006	+5.228	<.001	.005	3	1
LARGE_INTESTINE	EIF3L →	+0.705	+3.257	<.001	.002	3	1
LARGE_INTESTINE	HSCB →	+0.650	+3.212	.001	.006	3	1
LARGE_INTESTINE	TIMM9 →	+0.482	+3.064	.007	.009	3	1
LARGE_INTESTINE	CLUAP1 →	+0.697	+3.385	.001	.004	3	1
LARGE_INTESTINE	RAB3A →	+1.000	+3.299	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 139 associations by consensus.

Exploration

OTUD6A survival (RNA) · tumor vs normal (RNA) · all OTUD6A data types